100-300 kHz 电磁波会干扰有丝分裂过程,在细胞分裂的最终阶段使细胞器和后含物发生电泳,这意味着它可以杀伤正在分裂的干细胞或减数分裂的生殖细胞,但它同时也会抑制癌细胞的分裂,所以现在有的医院会用 150-200kHz 频段的电磁波治疗脑瘤、脑癌,利用的是脑内正常细胞不经常分裂,以及肿瘤 /癌细胞分裂较为频繁的特点。
无线充电:根据 QI 标准 1.2.4,发射端根据频率变化可以分为定频架构与变频架构。变频架构的工作原理是通过改变工作频率从而调节发射功率,改变的频率一般在 100-205kHz。定频架构,如苹果 MFi 认证的 7.5W 快充工作频率则固定在 127kHz 左右。
下面是关于电场疗法的一些论文
金兰瑞,李开华,辛育龄.肿瘤电化疗. 肿瘤[J].1991,5 (11-3).141~142
姚陈果,孙才新,米彦,熊兰,胡丽娜,胡娅.陡脉冲对恶性肿瘤细胞增殖及细胞周期的影响.生物医学工程学杂志[J].2004,21(4).546~548
Eva Nilsson,Henrikvon Euler,Jaak Berendson,et al. Electrochemical treatment of tumours. Bioelectrochemistry.51:1(2000), 2,1–11.doi:10.1016/S0302-4598(99)00073-2
Kai-hua Li, Yu-ling Xin, Yi-nong Gu, Bao-lan Xu, De-jun Fan, and Bang-fa Ni. Effects of direct current on dog liver possible mechanisms for tumor electrochemical treatment, Bioelectromagnetics.18:1,2–7 (1997). doi:10.1002/(sici)1521-186x(1997)18:1<2::aid-bem2>3.0.co;2-6
Vodovnik L., Miklavčič D., & Serša G. Modified cell proliferation due to electrical currents. Medical & Biological Engineering & Computing.30:4 (1992).CE21–CE28. doi:10.1007/bf02446174
Von Euler H., Olsson J. M., Hultenby K., Thörne A., & Lagerstedt A.-S. Animal models for treatment of unresectable liver tumours: a histopathologic and ultra-structural study of cellular toxic changes after electrochemical treatment in rat and dog liver. Bioelectrochemistry. 2003,59(1-2).89–98. doi:10.1016/s1567-5394(03)00006-9
Jaroszeski, M. J., Gilbert, R., & Heller, R. Electrochemotherapy: an emerging drug delivery method for the treatment of cancer. Advanced Drug Delivery Reviews. 1997,26(2-3), 185–197. doi:10.1016/s0169-409x(97)00034-3
Giardino, R., Fini, M., Bonazzi, V., Cadossi, R., Nicolini, A., & Carpi, A.Electrochemotherapy a novel approach to the treatment of metastatic nodules on the skin and subcutaneous tissues. Biomedicine & Pharmacotherapy. 60:8(2006).458–462. doi:10.1016/j.biopha.2006.07.016
Kirson, E. D., Gurvich, Z., Schneiderman, R., et al. Disruption of Cancer Cell Replication by Alternating Electric Fields. Cancer Research.64:9(2004,).3288–3295. doi:10.1158/0008-5472.can-04-0083
Kirson E.D., Dbalý V., Tovarys F., et al. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors.PNAS.June 12,2007.104:24.10152–10157.doi:10.1073/pnas.0702916104
Angela M. Davies, Uri Weinberg, and Yoram Palti. Tumor treating fields: a new frontier in cancer therapy. New York Academy of Sciences. 1291 (2013) 86–95. doi: 10.1111/nyas.12112
Stupp, R., Wong, E. T., Kanner, A. A., et al. NovoTTF-100A versus physician’s choice chemotherapy in recurrent glioblastoma: A randomised phase III trial of a novel treatment modality. European Journal of Cancer.48:14 (2012),2192–2202. doi:10.1016/j.ejca.2012.04.011
Wolfgang Wick. TTFields: where does all the skepticism come from? Neuro-Oncology.18:3(2016), 303–305. doi:10.1093/neuonc/now012
Toms, S. A., Kim, C. Y., Nicholas, G., & Ram, Z. Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial. Journal of Neuro-Oncology.141:2(2018),467–473. doi:10.1007/s11060-018-03057-z
Stupp, R., Taillibert, S., Kanner, A.,et al. Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma. JAMA.2017.318(23).2306–2316. doi:10.1001/jama.2017.18718
Denise Fabian, Maria del Pilar Guillermo Prieto Eibl, Iyad Alnahhas, et al.Treatment of Glioblastoma (GBM) with the Addition of Tumor-Treating Fields (TTF): A Review.Cancers.2019, 11(2), 174. doi: 10.3390/cancers11020174.
Gregory F. Guzauskas, Erqi L. Pollom, Volker W. Stieber, Bruce C. Wang, Lou Garrison. Tumor treating fields treatment for patients with newly diagnosed glioblastoma: A cost-effectiveness analysis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14–18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr LB-257.doi: 10.1158/1538-7445.AM2018-LB-257
顺便说下据我所知的其它频段电磁波的影响,高频电磁波,譬如 X 射线,伽马射线,可以把 DNA 打断,所以对人体有害,不过同理也可以用伽马射线来治疗癌症病灶。 紫外线频段的电磁波,剂量够大的情况下可能导致皮肤癌。 可见光频段的电磁波,强度够大的话可能导致人眼失明。 红外线频段的电磁波,强度够大的话会导致表面灼伤。 微波频段的电磁波,强度够大的话会导致体内灼伤。
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